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Hesperidin is an abundant and inexpensive
2022-03-29
Hesperidin is an abundant and inexpensive plant flavonoid, largely derived from citrus species including sweet orange and lemon. Hesperetin (Hst) is the aglycone of hesperidin. Hesperidin and hesperetin have been reported to show a battery of pharmacological properties, including anti-hyperlipidemic
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Our experimental results demonstrated http www apexbt com me
2022-03-29
Our experimental results demonstrated marked variability in antioxidant defenses and oxidative damage in Crassostrea gigas between the visceral mass and the gill after the treatments by rifampicin and verapamil through determining the changes of the activity of SOD and POD and MT content. It has bee
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We next compared the enhancing effects of nM
2022-03-29
We next compared the enhancing effects of 100nM zinc on currents produced by a low concentration of glycine with zinc effects on the same currents produced by the partial agonist taurine. In this experiment, zinc was co-applied with concentrations of glycine or taurine producing 5–10% of the maximal
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Introduction The hypoglossal nucleus is the
2022-03-29
Introduction The hypoglossal nucleus is the nucleus of the twelfth cranial nerve and is located on both sides of the mid line in the dorsal medulla oblongata and is situated between the proximal end of the medullary central canal and the beginning of the fourth ventricle (Tomasch and Etemadi, 1962)
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After brain injury adenosine levels rapidly increase in
2022-03-29
After brain injury, adenosine levels rapidly increase in the brain [9,10]. As shown in our previous studies, the increased adenosine concentration acts on adenosine A2A receptors (A2ARs), increasing post-traumatic glutamate levels in the brain and exacerbating the severity of injuries [11,12]. Accor
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Altretamine br Methods br Results br Discussion Significant
2022-03-29
Methods Results Discussion Significant alterations in the expression of genes related to the glutamatergic system have been shown in several experimental models of epilepsy; however, in most studies focused on acute changes or modifications in expression, these were investigated during the
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br GLP R expression in the vascular endothelium Immunohistoc
2022-03-29
GLP-1R expression in the vascular endothelium Immunohistochemistry studies utilizing GLP-1R antibodies that have now been demonstrated to be non-specific [46], initially identified GLP-1R protein expression in both mouse mesenteric artery SMCs and heart coronary SMCs [7]. However, evidence for VS
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The NVC response in the diseased or
2022-03-29
The NVC response in the diseased or aging PPDA may be altered, including changes in both the chemical mediators of NVC, ion channel behaviour, and the dynamics of the vascular system. For example, in Alzheimer’s disease the production of NO is shown to be inhibited (Lourenço et al., 2014), hyperten
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br Ethics approval br Availability of data and materials
2022-03-29
Ethics approval Availability of data and materials Consent for publication Competing interests Authors contributions Introduction Glucose supply to tissues is maintained through a complex regulatory network mostly driven by the pancreatic hormones insulin and glucagon which control
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GLP is released in response to
2022-03-29
GLP-1 is released in response to ingestion of nutrients including carbohydrates, protein, and fat. Recent studies aimed at identifying the receptors involved in nutrient stimulated GLP-1 secretion have identified free fatty Cy5 amine (non-sulfonated) receptor 4 (FFA4/GPR120) as a potential 7TM rece
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br Materials and methods br
2022-03-29
Materials and methods Results and discussion In order to identify genes required for photoautotrophic growth, we screened a random insertion mutant library of Synechocystis 6803 and obtained many mutants with impaired photoautotrophic growth. About 6000 random insertion colonies of the mutant
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The EZH overexpression group exhibited upregulated CEP expre
2022-03-28
The EZH2 overexpression group exhibited upregulated CEP55 expression but downregulated methylation, suggesting that changes in EZH2 expression in lung adenocarcinoma result in differences of CEP55 methylation and expression. Moreover, according to TCGA database and GSE27262 chip data, CEP55 expressi
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This study appears to provide
2022-03-28
This study appears to provide an additional example, albeit an unanticipated one, of the importance of renal ETB receptor function in the normal control of blood pressure and salt and water homeostasis. ETB receptor-deficient rats, collecting duct-specific ETB receptor knockout mice, and rats chroni
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Antigen presentation of incoming viral particles
2022-03-28
Antigen presentation of incoming viral particles has been well studied for diverse viruses in antigen-presenting cells (APCs), mostly in dendritic cells and macrophages in the context of the exogenous antigens’ pathway to prime the CD8+ T cells. However, CD4+ T cells are not known as efficient APCs,
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Cdk1/2 Inhibitor III receptor br Results br Discussion The p
2022-03-28
Results Discussion The present findings outline a novel regulatory mechanism for fasting-induced ketogenesis, which involves histamine release from mast Cdk1/2 Inhibitor III receptor into the hepatic portal system, H1 receptor-mediated stimulation of liver OEA biosynthesis, and recruitment of
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