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br Conflicts of interest br Funding
2024-08-16
Conflicts of interest Funding Introduction Brassicaceae is an economically important family of plants containing rapeseed, cabbage, broccoli, brussels, radish and mustard. Among them rapeseed plays a crucial role, because of its application in food and also in fuel industry. According to th
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br Liver specific AHR deficiency and energy balance
2024-08-16
Liver-specific AHR deficiency and energy balance In contrast to the amelioration of hepatic steatosis by global AHR deficiency, targeted knockout of Ahr in hepatocytes exacerbated it in B6 mice fed on a high-fat diet, without interfering with body weight gain [21]. This appeared to result from au
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Since non lipoprotein derived free cholesterol
2024-08-16
Since non-lipoprotein-derived free cholesterol is recycled from the plasma membrane through the endosomal system through receptor-independent mechanisms, we wanted to determine whether ABCA2 could alter the trafficking of this source of free cholesterol. Our approach was to measure the effect of mob
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Moreover an increase of extracellular calcium stimulates BMP
2024-08-16
Moreover, an increase of extracellular calcium stimulates BMP-2 expression of pulp Ginsenoside Rb1 via L-type calcium channel and ERK signaling, which can be attenuated by PD98059 and nifedipine . Dental pulp cells expressed little calcium-sensing receptors . immunohistochemistry staining also sho
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Since forskolin is known to act directly at the catalytic
2024-08-16
Since forskolin is known to act directly at the catalytic site of adenylate cyclases near the ATP binding (Tesmer et al., 1997), the synergistic and/or permissive effect of gonadotropins on FSK activity must occur at the level of AC itself or very near, at the level of one of its direct partner. The
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Curcumin is the principal natural polyphenol curcuminoid of
2024-08-16
Curcumin is the principal natural polyphenol curcuminoid of turmeric (Curcuma longa) rhizome, a member of the ginger family (Zingiberaceae) [13]. Curcumin has a wide spectrum of therapeutic properties, and it has been shown to possess antioxidant, anti-inflammatory, anticancer, antiangiogenesis, che
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Several studies have recently used optogenetics to selective
2024-08-16
Several studies have recently used optogenetics to selectively activate various cholinergic neurons (Jiang et al., 2014). However, most do not explicitly report direct release of GABA from cholinergic fibers, with the exception of our two studies described above (Saunders et al., 2015a, Saunders et
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The indirect effect of corporate taxation as given by the
2024-08-16
The indirect effect of corporate taxation, as given by the second term in Eq. (18), consists of two elements; (i) a standard Fludara effect (τ/n2), and (ii) a capital cost effect (rG(1−αt)/(1−t)). With a CRS technology, the cost effect vanishes, whereas with an IRS (a DRS) technology the cost effec
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The indirect effect of corporate taxation as given by the
2024-08-16
The indirect effect of corporate taxation, as given by the second term in Eq. (18), consists of two elements; (i) a standard vadadustat effect (τ/n2), and (ii) a capital cost effect (rG(1−αt)/(1−t)). With a CRS technology, the cost effect vanishes, whereas with an IRS (a DRS) technology the cost ef
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Regarding androgens it is known
2024-08-16
Regarding androgens, it is known that they are also essential for reproductive success (Walters et al., 2010). At the molecular level, their effects are produced mainly by dihydrotestosterone (DHT), arising from the conversion of testosterone by the enzyme 3-oxo-5-alpha-steroid-4-dehydrogenase (enco
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Physiological total plasma LPA levels are
2024-08-15
Physiological total plasma LPA levels are normally less than 1μM in healthy subjects. LPA levels have been reported to be increased in malignant effusions or plasma in cancer patients [20]. In addition, increasing ATX activity detected in healthy pregnant women in the third trimester of pregnancy ex
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On the contrary evidence also suggests
2024-08-15
On the contrary, evidence also suggests that autophagy plays a striking protective role in cancer cells. Highly burgeoning cancer Ivachtin require cellular building blocks for their metabolism and energy production. At this stage of cancer development, autophagy acts as a friend providing all the e
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Roles of Aurora kinases in directly activating
2024-08-15
Roles of Aurora kinases in directly activating multiple oncogenic pathways and promoting proliferation as well as transformation have also been demonstrated. Aurora-A has been shown to up-regulate telomerase reverse transcriptase mRNA through c-myc [26]. The kinase was also implicated in activating
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br Results br Discussion br
2024-08-15
Results Discussion Conclusion The flux of glucose into cytosolic short chain acyl-CoAs was maintained in pure beta gsk3b inhibitor in the presence of inhibition of ATP citrate lyase with hydroxycitrate and also in a cell line with >90% ATP citrate lyase knockdown suggesting that a pathway
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Introduction Preeclampsia a serious hypertensive disorder
2024-08-15
Introduction Preeclampsia, a serious hypertensive disorder that can occur during pregnancy, is a pregnancy-related disease characterized by the onset of monocarboxylate transporters and proteinuria after the 20 t h week of gestation, and it occurs in about 5% of all pregnancies [1]. If left untrea
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