• This trial included patients who met the ICD criteria

  2019-06-11

  

  This trial included 1500 patients, who met the ICD criteria for primary prevention (non-ischemic, ischemic, dual chamber ICD or CRT-D). The patients were randomized to 3 arms: (1) conventional therapy: Zone 1(VT) 170bpm, 2.5s delay, Zone 2 (VF) 200bpm, 1s delay; (2) high rate therapy: Zone 1(VT) 170

• Others have observed the marked

  2019-06-11

  

  Others have observed the marked differences in clinicopathological characteristics between breast cancer subtypes by IHC study. However, they reported that triple negative and HER2 patients are at high risk of recurrences after adjusting for age, stage and histological grade. Our data support this o

• br Material and Methods br Results br Discussion Radiofreque

  2019-06-11

  

  Material and Methods Results Discussion Radiofrequency ablation has a long history of use. It has been used especially in the neurosurgical field [8,9]. Rosenthal described the first ablations in bone 20 years ago [5]. Technically the radiofrequency generator forms an electric current leadi

• br Discovery of S PR as

  2019-06-11

  

  Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than

• Several mechanisms have been proposed Due to a greater birth

  2019-06-11

  

  Several mechanisms have been proposed. Due to a greater birth interval, children who are breastfed will enjoy a greater period of exclusive parental attention as either the only child or youngest child. This exclusivity might have an effect on intelligence. It has been consistently observed that the

• Sildenafil mesylate En este mapeo las revistas que se

  2019-06-11

  

  En este mapeo, las revistas que se destacan son Polis, de la Universidad Bolivariana de Chile, con 28 trabajos que mencionan Sildenafil mesylate Morin, Educere, de la Universidad de los Andes de Venezuela, con 17 artículos que citan a Morin, y EccoS, de la Universidade Nove de Julho (uninove) de Bra

• Romiplostim is an Fc fusion

  2019-06-11

  

  Romiplostim is an Fc-fusion protein that augments thrombopoiesis by binding to and activating the thrombopoietin receptor. It is approved for the treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpura who have had an insufficient response to corticosteroids, immunoglo

• br Among the most important findings to have

  2019-06-11

  

  Among the most important findings to have emerged from the massive 2013–16 outbreak of Ebola virus disease in west Africa is the delayed clearance of virus from the semen of men who survived the disease and the consequent risk of sexual transmission of the virus, although this seems to be rare. In

• WHO estimates that of people

  2019-06-11

  

  WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for

• It is recommended that pilsicainide

  2019-06-11

  

  It is recommended that pilsicainide be administered over 10min, with 1.0mg/kg being the maximum daily dosage allowed. However, a single oral dose of pilsicainide has been shown to be effective, feasible and safe, and the single dose is always from 100 to 150mg [4,10]. Both the time to maximum drug c

• br Conflict of interest statement br

  2019-06-11

  

  Conflict of interest statement Acknowledgments The authors would like to thank Dr. Bjørn Naume, and Dr. Erik Løkkevik from the Department of Clinical Oncology, the Norwegian Radium Hospital for their helpful comments. This study was supported by grants from the Norwegian Radium Hospital Founda

• An interesting finding in the study of Ngabo and colleagues

  2019-06-10

  

  An interesting finding in the study of Ngabo and colleagues was that, after a huge drop in the number of admittances to hospital for rotavirus in 2013, there was no further fall the next year. As the researchers discuss, this finding might herald the beginning of a biennial pattern of rotavirus acti

• LQT can have numerous clinical manifestations ranging from n

  2019-06-10

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• cyclosporin Preamble The J wave syndromes

  2019-06-10

  

  Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology cyclosporin over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1992 [

• La antinomia de los signos d a y noche que

  2019-06-10

  

  La antinomia de los signos “día” y “noche”, que comienza desde las metáforas del título, sugiere una rotación que se opera en el orden cósmico. El momento diurno tiene que ceder necesariamente el paso AL 8697 la noche, en una sucesión sin la cual cada uno de los elementos tomado aisladamente perderí

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