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In recent years there has been growing interest
2019-04-22
In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR
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br En el ciclo de
2019-04-20
En el ciclo de novelas que de una forma u otra giran alrededor de la violencia y del narcotráfico, Cóbraselo caro atraviesa todos esos textos para preguntarse, por un lado, por la génesis de la violencia mexicana y por otro, para manifestar el deseo de una limpieza hallada en el modelo de mundo de
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br Al comienzo de Elizabeth Corral
2019-04-20
Al comienzo de , Elizabeth Corral afirma que “la escritura de Sergio Pitol tiene una relación orgánica con otras artes” (11). El resto del libro es la comprobación de esta tesis, un recorrido abiertamente personal en el que destacan el ingenio de la mirada y la lucidez para desmenuzar cada uno de
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The work by Fumiaki Imamura and colleagues in
2019-04-20
The work by Fumiaki Imamura and colleagues in this issue of is a unique attempt to evaluate measures of dietary quality and their trends in most countries worldwide. They used a wide range of data sources, including nationally representative dietary surveys, local surveys, and foods disappearance da
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br Conclusion br Conflict of interest br Introduction
2019-04-20
Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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Introduction Osteosarcoma OS is the most commonly diagnosed
2019-04-20
Introduction Osteosarcoma (OS) is the most commonly diagnosed histological form of primary bone tumor with high morbidity, and it is mainly prevalent in teenagers and young people [1]. Pain is the most common early symptom of OS and can cause fracture of the affected bone. Currently, multiple thera
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Changing the pacemaker mode to VDD is a good approach
2019-04-20
Changing the pacemaker mode to VDD is a good approach in cases of normal sinus node function and loss of atrial lead capture, especially if atrial sensing is stable. In this case, Short AV delay is a good way to reduce the risk of R on T phenomenon which is theoretically possible if a ventricular ec
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br Although much attention centres on Afghanistan
2019-04-20
Although much attention centres on Afghanistan\'s political and security transitions, malnutrition is a foremost concern. Because an absence of adequate nutrition has crucial long-term effects on individuals and on social and economic development, nutrition rates in Afghanistan deserve attention a
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br The west African outbreak of Ebola virus disease
2019-04-20
The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s
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De esta poca son los primeros testimonios de la idea
2019-04-20
De esta época son los primeros testimonios de la idea de fundar un periódico en París: en una carta del 7 de agosto de 1848, Eugène Carpentier, futuro administrador de La Tribune des Peuples, le presenta Ki16425 Mickiewicz un presupuesto estimado de lo que costaría un periódico. De cualquier manera,
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br The world population faces
2019-04-20
The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures
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Although the study is of a high
2019-04-20
Although the study is of a high quality given the constraints of the case-control design, we question whether it alone provides sufficient evidence for this policy recommendation. Observational studies of ITNs are notoriously fraught with challenges. Even in settings in which randomised trials show
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br Discussion In the present report we describe a
2019-04-19
Discussion In the present report, we describe a technique for the ARCA of a 6.0 Fr active fixation atrial lead in the inferior IAS using a 9.0 Fr GC. Previous studies have indicated that inferior IAS pacing significantly reduces paroxysmal AF burden and recurrence and slows the progression to ch
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The BrS ECG is often widely dynamic with
2019-04-19
The BrS ECG is often widely dynamic, with ST segment elevations that fluctuate from hour to hour, day to day, and month to month. Diurnal variation shows that events occur more frequently at night during periods of high vagal tone [2]. In some patients, the use of frequent ECGs or 12-lead ambulatory
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The effects of zoledronic acid are most
2019-04-19
The effects of zoledronic clofibrate are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Wher
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